PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27207556-0 2016 A Glycine-Insulin Autocrine Feedback Loop Enhances Insulin Secretion From Human beta-Cells and Is Impaired in Type 2 Diabetes. Glycine 2-9 insulin Homo sapiens 10-17 27207556-0 2016 A Glycine-Insulin Autocrine Feedback Loop Enhances Insulin Secretion From Human beta-Cells and Is Impaired in Type 2 Diabetes. Glycine 2-9 insulin Homo sapiens 51-58 27207556-6 2016 beta-Cells exhibit significant glycine-induced Cl(-) currents that promote membrane depolarization, Ca(2+) entry, and insulin secretion from beta-cells from donors without T2D. Glycine 31-38 insulin Homo sapiens 118-125 27207556-9 2016 Finally, a significant positive relationship exists between insulin and GlyR, because insulin enhances the glycine-activated current in a phosphoinositide 3-kinase-dependent manner, a positive feedback loop that we find is completely lost in beta-cells from donors with T2D. Glycine 107-114 insulin Homo sapiens 60-67 27207556-9 2016 Finally, a significant positive relationship exists between insulin and GlyR, because insulin enhances the glycine-activated current in a phosphoinositide 3-kinase-dependent manner, a positive feedback loop that we find is completely lost in beta-cells from donors with T2D. Glycine 107-114 insulin Homo sapiens 86-93