Title : Effects of primary metabolites of organophosphate flame retardants on transcriptional activity via human nuclear receptors.

Pub. Date : 2016 Mar 14

PMID : 26778350






1 Functional Relationships(s)
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1 In addition, these hydroxylated TPHP-metabolites also showed ERbeta antagonistic activity at higher concentrations and exhibited pregnane X receptor (PXR) agonistic activity as well as androgen receptor (AR) and glucocorticoid receptor (GR) antagonistic activities at similar levels to those of TPHP. triphenyl phosphate estrogen receptor 2 Homo sapiens