Pub. Date : 2016 Mar
PMID : 26691294
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | BACKGROUND: The cardiac glycoside digitoxin preferentially inhibits the growth of breast cancer cells and targets the Erk pathway. | Digitoxin | mitogen-activated protein kinase 1 | Homo sapiens |
| 2 | Digitoxin activates expression of Erk pathway genes and suppresses expression of IAP genes. | Digitoxin | mitogen-activated protein kinase 1 | Homo sapiens |
| 3 | CONCLUSION: Digitoxin appears to act through the Erk and stress response pathways and is worthwhile to study to prevent and treat cancer. | Digitoxin | mitogen-activated protein kinase 1 | Homo sapiens |