Title : Toll-like receptor 4-induced endoplasmic reticulum stress contributes to impairment of vasodilator action of insulin.

Pub. Date : 2015 Nov 1

PMID : 26522062






4 Functional Relationships(s)
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1 Saturated fatty acids (SFA) activate TLR4, which induces ER stress and endothelial dysfunction. Fatty Acids toll-like receptor 4 Mus musculus
2 Saturated fatty acids (SFA) activate TLR4, which induces ER stress and endothelial dysfunction. Fatty Acids toll-like receptor 4 Mus musculus
3 Therefore, we determined whether TLR4-mediated ER stress is an obligatory step mediating SFA-induced endothelial dysfunction. Fatty Acids toll-like receptor 4 Mus musculus
4 Taken together, the results suggest that TLR4-induced ER stress may be an obligatory step mediating the SFA-mediated endothelial dysfunction. Fatty Acids toll-like receptor 4 Mus musculus