Title : Activation of AMPK improves inflammation and insulin resistance in adipose tissue and skeletal muscle from pregnant women.

Pub. Date : 2015 Dec

PMID : 26407807






1 Functional Relationships(s)
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1 Activation of AMPK, using two pharmacologically distinct compounds, AICAR or phenformin, significantly suppressed LPS- or IL-1beta-induced gene expression and secretion of pro-inflammatory cytokine IL-6, the chemokines IL-8 and MCP-1, and COX-2 and subsequent prostaglandin release from adipose tissue and skeletal muscle. Phenformin protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens