Pub. Date : 2015 Oct 15
PMID : 26256075
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In mouse studies, nonselective nAChR antagonist mecamylamine blocks cocaine-induced conditioned place preference (CPP) and behavioral sensitization. | Cocaine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |
| 2 | Among subtype-selective nAChR antagonists, the beta2-selective antagonist dihydrobetaerythroidine and alpha7 antagonist methyllycaconitine (MLA), but not MLA alone prevent behavioral sensitization to cocaine. | Cocaine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |
| 3 | Among subtype-selective nAChR antagonists, the beta2-selective antagonist dihydrobetaerythroidine and alpha7 antagonist methyllycaconitine (MLA), but not MLA alone prevent behavioral sensitization to cocaine. | Cocaine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |
| 4 | These results indicate that the alpha3beta4 nAChR play a role in the rewarding and behavioral effects of cocaine, and that selective alpha3beta4 nAChR ligands can attenuate cocaine-induced behavioral phenomena. | Cocaine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |
| 5 | These results indicate that the alpha3beta4 nAChR play a role in the rewarding and behavioral effects of cocaine, and that selective alpha3beta4 nAChR ligands can attenuate cocaine-induced behavioral phenomena. | Cocaine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |
| 6 | These results indicate that the alpha3beta4 nAChR play a role in the rewarding and behavioral effects of cocaine, and that selective alpha3beta4 nAChR ligands can attenuate cocaine-induced behavioral phenomena. | Cocaine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |