Title : Oligonucleotide gap-fill ligation for mutation detection and sequencing in situ.

Pub. Date : 2015 Dec 15

PMID : 26240388






1 Functional Relationships(s)
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1 To demonstrate the clinical applicability of our assay, we show specific detection of a point mutation in the EGFR gene in fresh frozen and formalin-fixed, paraffin-embedded (FFPE) lung cancer samples and confirm the detected mutation by in situ sequencing. Paraffin epidermal growth factor receptor Homo sapiens