Title : Cytotoxic Synergy Between Cytokines and NSAIDs Associated With Idiosyncratic Hepatotoxicity Is Driven by Mitogen-Activated Protein Kinases.

Pub. Date : 2015 Aug

PMID : 25953702






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Treatment with a representative AA or PA derivative induced activation of the MAPKs c-Jun N-terminal kinase (JNK), extracellular signal-regulated kinase (ERK), and p38. propionic acid mitogen-activated protein kinase 1 Homo sapiens
2 Treatment with a representative AA or PA derivative induced activation of the MAPKs c-Jun N-terminal kinase (JNK), extracellular signal-regulated kinase (ERK), and p38. propionic acid mitogen-activated protein kinase 1 Homo sapiens
3 In contrast, an ERK inhibitor potentiated cytotoxicity from cytokine interactions with PA derivatives. propionic acid mitogen-activated protein kinase 1 Homo sapiens