Title : Ventral tegmental area cholinergic mechanisms mediate behavioral responses in the forced swim test.

Pub. Date : 2015 Jul 15

PMID : 25865152






1 Functional Relationships(s)
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1 Here, male Sprague-Dawley rats received systemic or VTA-specific administration of the acetylcholinesterase inhibitor, physostigmine (systemic; 0.06 or 0.125mg/kg, intra-cranial; 1 or 2mug/side), the muscarinic acetylcholine receptor (AChR) antagonist scopolamine (2.4 or 24mug/side), or the nicotinic AChR antagonist mecamylamine (3 or 30mug/side), prior to the FST test session. Physostigmine acetylcholinesterase Rattus norvegicus