Protein Name acetylcholinesterase
Organism Rattus norvegicus
Gene ID 83817
Gene Symbol


UniProt P37136 (ACES_RAT), Q505J2 (Q505J2_RAT)
Relationships Total Number of functionally related compound(s) : 1302
Total Number of Articles : 2270


Gene Summary

Enables acetylcholine binding activity; acetylcholinesterase activity; and choline binding activity. Involved in several processes, including acetylcholine catabolic process; positive regulation of neurogenesis; and response to insulin. Located in several cellular components, including endoplasmic reticulum; neuronal cell body; and synaptic membrane. Is active in neuromuscular junction and synaptic cleft. Biomarker of acute stress disorder and leptospirosis. Human ortholog(s) of this gene implicated in Alzheimer's disease; epilepsy; and myasthenia gravis. Orthologous to human ACHE (acetylcholinesterase (Cartwright blood group)). [provided by Alliance of Genome Resources, Apr 2022]

  • acetylcholinesterase
  • glycolipid-anchored form of acetylcholinesterase
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