Title : HSP90 inhibitor AUY922 induces cell death by disruption of the Bcr-Abl, Jak2 and HSP90 signaling network complex in leukemia cells.

Pub. Date : 2015 Jan

PMID : 25821558






1 Functional Relationships(s)
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1 Tyrosine phosphorylation of Bcr-Abl showed a dose-dependent decrease in 32Dp210T315I following AUY922 treatment for 16h. Tyrosine ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens