PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25753330-0 2015 Novel curcumin analogs to overcome EGFR-TKI lung adenocarcinoma drug resistance and reduce EGFR-TKI-induced GI adverse effects. Curcumin 6-14 epidermal growth factor receptor Homo sapiens 35-39 25753330-0 2015 Novel curcumin analogs to overcome EGFR-TKI lung adenocarcinoma drug resistance and reduce EGFR-TKI-induced GI adverse effects. Curcumin 6-14 epidermal growth factor receptor Homo sapiens 91-95 25753330-1 2015 Curcumin (1) down-regulates the expression as well as phosphorylation of epidermal growth factor receptor (EGFR) in lung adenocarcinoma cells expressing gefitinib-resistant EGFR. Curcumin 0-8 epidermal growth factor receptor Homo sapiens 73-105 25753330-1 2015 Curcumin (1) down-regulates the expression as well as phosphorylation of epidermal growth factor receptor (EGFR) in lung adenocarcinoma cells expressing gefitinib-resistant EGFR. Curcumin 0-8 epidermal growth factor receptor Homo sapiens 107-111 25753330-1 2015 Curcumin (1) down-regulates the expression as well as phosphorylation of epidermal growth factor receptor (EGFR) in lung adenocarcinoma cells expressing gefitinib-resistant EGFR. Curcumin 0-8 epidermal growth factor receptor Homo sapiens 173-177 25753330-6 2015 Among all evaluated curcumin derivatives, compound 2 showed the best inhibitory effects on both wild-type and mutant EGFR by efficiently inducing gefitinib-insensitive EGFR degradation. Curcumin 20-28 epidermal growth factor receptor Homo sapiens 117-121