Title : [Development of physical dependence on nicotine and endogenous opioid system--participation of α7 nicotinic acetylcholine receptor].

Pub. Date : 2014 Oct

PMID : 25651617






6 Functional Relationships(s)
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Protein Name
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1 Nicotine (NIC) regulates various cellular functions acting on the nicotinic acetylcholine receptor (nAChR). Nicotine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
2 Nicotine (NIC) regulates various cellular functions acting on the nicotinic acetylcholine receptor (nAChR). Nicotine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
3 Nicotine (NIC) regulates various cellular functions acting on the nicotinic acetylcholine receptor (nAChR). Nicotine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
4 Nicotine (NIC) regulates various cellular functions acting on the nicotinic acetylcholine receptor (nAChR). Nicotine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
5 Moreover, NIC-induced antinociception was antagonized by both alpha 4 beta 2 and alpha 7 nAChR antagonists, while NIC-induced HPA axis activation was antagonized by alpha 4 beta 2 nAChR antagonist, but not by alpha 7 nAChR antagonist. Nicotine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
6 Moreover, NIC-induced antinociception was antagonized by both alpha 4 beta 2 and alpha 7 nAChR antagonists, while NIC-induced HPA axis activation was antagonized by alpha 4 beta 2 nAChR antagonist, but not by alpha 7 nAChR antagonist. Nicotine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus