Pub. Date : 2014 Jul 1
PMID : 25642303
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Our results also suggest that interfering effect of metformin on cisplatin may be also through upregulation of Akt. | Metformin | AKT serine/threonine kinase 1 | Homo sapiens |
2 | Regarding the pivotal role of Akt in drug resistance, it may be reasonable to conclude that the antagonistic effect of metformin on cisplatin effect may be through this central mediator of drug resistance. | Metformin | AKT serine/threonine kinase 1 | Homo sapiens |