PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25642303-7 2014 Our results also suggest that interfering effect of metformin on cisplatin may be also through upregulation of Akt. Metformin 52-61 AKT serine/threonine kinase 1 Homo sapiens 111-114 25642303-8 2014 Regarding the pivotal role of Akt in drug resistance, it may be reasonable to conclude that the antagonistic effect of metformin on cisplatin effect may be through this central mediator of drug resistance. Metformin 119-128 AKT serine/threonine kinase 1 Homo sapiens 30-33