Pub. Date : 2015
PMID : 25553117
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Parthenolide inhibits cancer stem-like side population of nasopharyngeal carcinoma cells via suppression of the NF-kappaB/COX-2 pathway. | parthenolide | nuclear factor kappa B subunit 1 | Homo sapiens |
| 2 | In addition, parthenolide exhibited an inhibitory effect on nuclear factor-kappa B (NF-kappaB) nucler translocation by suppressing both the phosphorylation of IkappaB kinase complex and IkappaBalpha degradation. | parthenolide | nuclear factor kappa B subunit 1 | Homo sapiens |
| 3 | In addition, parthenolide exhibited an inhibitory effect on nuclear factor-kappa B (NF-kappaB) nucler translocation by suppressing both the phosphorylation of IkappaB kinase complex and IkappaBalpha degradation. | parthenolide | nuclear factor kappa B subunit 1 | Homo sapiens |
| 4 | Taken together, these results suggest that parthenolide may exert its cancer stem cell-targeted chemotherapy through the NF-kappaB/COX-2 pathway. | parthenolide | nuclear factor kappa B subunit 1 | Homo sapiens |