Title : The kinetics of steroidogenesis activator polypeptide in the rat adrenal cortex. Effects of adrenocorticotropin, cyclic adenosine 3':5'-monophosphate, cycloheximide, and circadian rhythm.

Pub. Date : 1989 Sep 15

PMID : 2549056






2 Functional Relationships(s)
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1 Of the rat tissues examined, only the major steroid-forming organs (adrenal cortex and gonads) had significant levels of immunoreactive, cAMP-responsive SAP, while cAMP-unresponsive immunoreactivity was also detectable in the thymus, spleen, and brain. Cyclic AMP heat shock protein family A (Hsp70) member 5 Rattus norvegicus
2 Considered together with the biological activity previously demonstrated for SAP in vitro, these data are consistent with its role as a cAMP-dependent, cycloheximide-sensitive modulator of steroid biosynthesis. Cyclic AMP heat shock protein family A (Hsp70) member 5 Rattus norvegicus