Title : Ketoconazole inhibits self-induced metabolism of 1,25-dihydroxyvitamin D3 and amplifies 1,25-dihydroxyvitamin D3 receptor up-regulation in rat osteosarcoma cells.

Pub. Date : 1989 Aug 1

PMID : 2546501






1 Functional Relationships(s)
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1 In cells treated with both 1,25-[3H]D3 and ketoconazole, up-regulation of VDR was increased by 40% over that observed with cells receiving 1,25-[3H]D3 alone. Cholecalciferol vitamin D receptor Rattus norvegicus