Title : A chemical tuned strategy to develop novel irreversible EGFR-TK inhibitors with improved safety and pharmacokinetic profiles.

Pub. Date : 2014 Dec 11

PMID : 25409491






1 Functional Relationships(s)
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1 Incorporation of these olefins into the quinazoline templates produced potent EGFR inhibitors with improved safety and pharmacokinetic properties. Quinazolines epidermal growth factor receptor Homo sapiens