Pub. Date : 2015 Mar
PMID : 25376731
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The present study aimed to investigate whether TGF-beta was involved in DHM-triggered cell-viability inhibition and apoptosis induction. | dihydromyricetin | transforming growth factor, beta 1 | Mus musculus |
| 2 | TGF-beta expression was significantly decreased following DHM treatment. | dihydromyricetin | transforming growth factor, beta 1 | Mus musculus |
| 3 | In conclusion, the results of the present study defined and supported a novel function for DHM, indicating that it induced cell apoptosis by downregulating ROS production via the TGF-beta/Smad3 signaling pathway in mouse hepatocellular carcinoma Hepal-6 cells. | dihydromyricetin | transforming growth factor, beta 1 | Mus musculus |