Title : Metformin and erlotinib synergize to inhibit basal breast cancer.

Pub. Date : 2014 Nov 15

PMID : 25361177






2 Functional Relationships(s)
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Protein Name
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1 Combined metformin and erlotinib led to partial regression of PTEN-null and EGFR-amplified xenografted MDA-MB-468 BBC tumors with evidence of significant apoptosis, reduction of EGFR and AKT signaling, and lack of altered plasma insulin levels. Metformin epidermal growth factor receptor Homo sapiens
2 Combined metformin and erlotinib led to partial regression of PTEN-null and EGFR-amplified xenografted MDA-MB-468 BBC tumors with evidence of significant apoptosis, reduction of EGFR and AKT signaling, and lack of altered plasma insulin levels. Metformin epidermal growth factor receptor Homo sapiens