Title : Nucleolin enhances internal ribosomal entry site (IRES)-mediated translation of Sp1 in tumorigenesis.

Pub. Date : 2014 Dec

PMID : 25173817






2 Functional Relationships(s)
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1 Moreover, gefitinib, and LY294002 and MK2206 compounds inhibited IRES-mediated Sp1 translation, implying that activation of the epithelial growth factor receptor (EGFR) pathway via Akt activation triggers the IRES pathway. 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one epidermal growth factor receptor Homo sapiens
2 Moreover, gefitinib, and LY294002 and MK2206 compounds inhibited IRES-mediated Sp1 translation, implying that activation of the epithelial growth factor receptor (EGFR) pathway via Akt activation triggers the IRES pathway. 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one epidermal growth factor receptor Homo sapiens