Title : Quercetin, a natural dietary flavonoid, acts as a chemopreventive agent against prostate cancer in an in vivo model by inhibiting the EGFR signaling pathway.

Pub. Date : 2014 Oct

PMID : 25164625






3 Functional Relationships(s)
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1 Quercetin, a natural dietary flavonoid, acts as a chemopreventive agent against prostate cancer in an in vivo model by inhibiting the EGFR signaling pathway. Quercetin epidermal growth factor receptor Rattus norvegicus
2 EGFR, PI3K/Akt protein levels were significantly increased in chemically induced cancer rats, which were brought back to normalcy in both DLP & VP (dorsolateral prostate & ventral prostate) by quercetin supplementation. Quercetin epidermal growth factor receptor Rattus norvegicus
3 To conclude from the present study, quercetin was effective in preventing prostate cancer progression by inhibiting the EGFR signaling pathway and by regulating cell adhesion molecules in Sprague Dawley rats. Quercetin epidermal growth factor receptor Rattus norvegicus