Pub. Date : 2014
PMID : 24917394
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In silico approach to inhibition of tyrosinase by ascorbic acid using molecular docking simulations. | Ascorbic Acid | tyrosinase | Homo sapiens |
| 2 | In the present study, inhibitory effect of ascorbic acid against tyrosinase has been investigated and it has shown a remarkable inhibitory effect in in vitro assays. | Ascorbic Acid | tyrosinase | Homo sapiens |
| 3 | Then, the in silico-based experiments established through molecular docking calculations and scoring, docking search algorithm, and data plotting indicated that ascorbic acid is strong inhibitor of tyrosinase by interacting with four amino acid units (histidine 263, serine 282, phenylalanine 264, and valin 283) in the active site of the enzyme. | Ascorbic Acid | tyrosinase | Homo sapiens |