Title : Two amino acid residues confer different binding affinities of Abelson family kinase SRC homology 2 domains for phosphorylated cortactin.

Pub. Date : 2014 Jul 11

PMID : 24891505






1 Functional Relationships(s)
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1 We show that this significant affinity difference is due to the substitution of arginine 161 and serine 187 in Abl to leucine 207 and threonine 233 in Arg, respectively. Serine ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens