Title : The tyrosine kinase inhibitor dasatinib effectively blocks PDGF-induced orbital fibroblast activation.

Pub. Date : 2014 Jul

PMID : 24874745






2 Functional Relationships(s)
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1 Furthermore, orbital tissue was obtained from a patient with active GO, and the effect of dasatinib on the expression levels of HAS2-, CCL2-, IL6-, and IL8-mRNA expression was examined by real-time quantitative PCR. Dasatinib interleukin 6 Homo sapiens
2 In orbital tissue from active GO, dasatinib significantly suppressed HAS2-, CCL2-, IL6- and IL8-mRNA levels. Dasatinib interleukin 6 Homo sapiens