Title : 6-shogaol, a major compound in ginger, induces aryl hydrocarbon receptor-mediated transcriptional activity and gene expression.

Pub. Date : 2014 Jun 18

PMID : 24857157






2 Functional Relationships(s)
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1 Subsequently, the mRNA levels of AHR-targeting drug-metabolizing enzymes (CYP1A1, UGT1A1, and ABCG 2) and the protein level of CYP1A1 in HepG2 cells were shown to be increased by 6-shogaol. shogaol aryl hydrocarbon receptor Homo sapiens
2 This is the first report that 6-shogaol can regulate the expression of detoxification enzymes by AHR activation. shogaol aryl hydrocarbon receptor Homo sapiens