Title : Localization of cytochrome P450 and related enzymes in adult rat testis and downregulation by estradiol and bisphenol A.

Pub. Date : 2014 Jul

PMID : 24752506






1 Functional Relationships(s)
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1 Testicular CYP1B1 and CYP2A1 protein levels were decreased following treatment of adult rats with estradiol benzoate at 0.004, 0.04, 0.4, or 4 mumol/kg/day or bisphenol A at 400 or 800 mumol/kg/day, for 14 days, whereas expression of HSD3B was unaffected. estradiol 3-benzoate hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 Rattus norvegicus