Title : Synthetic triterpenoids can protect against toxicity without reducing the efficacy of treatment with Carboplatin and Paclitaxel in experimental lung cancer.

Pub. Date : 2014 Jan

PMID : 24659938






1 Functional Relationships(s)
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1 In an experimental model of lung cancer, the triterpenoids activated the Nrf2 pathway, as seen by induction of the cytoprotective enzyme NQO1, and reduced the toxicity of carboplatin and paclitaxel. Carboplatin NFE2 like bZIP transcription factor 2 Homo sapiens