Title : Effect of silibinin in reducing inflammatory pathways in in vitro and in vivo models of infection-induced preterm birth.

Pub. Date : 2014

PMID : 24647589






2 Functional Relationships(s)
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1 Fetal brains were collected after 6 h. In human fetal membranes, silibinin significantly decreased LPS-stimulated expression of IL-6 and IL-8, COX-2, and prostaglandins PGE2 and PGF2alpha. Silybin interleukin 6 Homo sapiens
2 Preterm fetal membranes with active infection treated with silibinin showed a decrease in IL-6, IL-8 and MMP-9 expression. Silybin interleukin 6 Homo sapiens