Title : A novel synthetic oleanane triterpenoid suppresses adhesion, migration, and invasion of highly metastatic melanoma cells by modulating gelatinase signaling axis.

Pub. Date : 2015 Aug

PMID : 24510625






1 Functional Relationships(s)
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Protein Name
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1 AMR-Me suppresses the activity of MT1-MMP, MMP-2, and MMP-9 by downregulation of VEGF/pFAK397 /pJNK/pERK/NF-kappaB and activation of TIMP-1 and TIMP-2 in metastatic melanoma cell line, B16F10. methyl 25-hydroxy-3-oxoolean-12-en-28-oate matrix metallopeptidase 14 (membrane-inserted) Mus musculus