| Protein Name | matrix metallopeptidase 14 (membrane-inserted) |
|---|---|
| Organism | Mus musculus |
| Gene ID | 17387 |
| Gene Symbol | Mmp14 |
| UniProt | P53690 (MMP14_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
77
Total Number of Articles : 78 |
Description |
matrix metallopeptidase 14 (membrane-inserted) |
| Gene Summary |
This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprotein undergoes proteolytic processing to generate a mature, zinc-dependent endopeptidase enzyme. Mice lacking the encoded protein exhibit craniofacial dysmorphism, arthritis, osteopenia, dwarfism, and fibrosis of soft tissues. [provided by RefSeq, Feb 2016] |
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| Properties | |