Pub. Date : 2014 Mar 1
PMID : 24462674
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Celecoxib offsets the negative renal influences of cyclosporine via modulation of the TGF-beta1/IL-2/COX-2/endothelin ET(B) receptor cascade. | Celecoxib | transforming growth factor, beta 1 | Rattus norvegicus |
| 2 | Together, the data suggest that the facilitation of the interplay between the TGF-beta1/IL-2/COX-2 pathway and the endothelin ET(B) receptors constitutes the cellular mechanism by which celecoxib ameliorates the nephrotoxic manifestations of CSA in rats. | Celecoxib | transforming growth factor, beta 1 | Rattus norvegicus |