Title : Unique effect of Cu(II) in the metal-induced amyloid formation of β-2-microglobulin.

Pub. Date : 2014 Mar 4

PMID : 24450572






1 Functional Relationships(s)
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1 In the presence of stoichiometric amounts of Cu(II), beta2m self-associates into discrete oligomeric species, including dimers, tetramers, and hexamers, before ultimately forming amyloid fibrils that contain no copper. Copper beta-2-microglobulin Homo sapiens