Title : Identification of secreted phosphoprotein 1 gene as a new rheumatoid arthritis susceptibility gene.

Pub. Date : 2015 Mar

PMID : 24448344






2 Functional Relationships(s)
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1 RESULTS: We provide evidence for a distinct contribution of SPP1 to RA susceptibility according to ACPA status: the combination of >=3 SPP1 rs11439060 and rs9138 common alleles was associated mainly with ACPA negativity (p=1.29x10(-5), ORACPA-negative 1.257 (1.135 to 1.394)) and less with ACPA positivity (p=0.0148, ORACPA-positive 1.072 (1.014 to 1.134)). oracpa secreted phosphoprotein 1 Homo sapiens
2 RESULTS: We provide evidence for a distinct contribution of SPP1 to RA susceptibility according to ACPA status: the combination of >=3 SPP1 rs11439060 and rs9138 common alleles was associated mainly with ACPA negativity (p=1.29x10(-5), ORACPA-negative 1.257 (1.135 to 1.394)) and less with ACPA positivity (p=0.0148, ORACPA-positive 1.072 (1.014 to 1.134)). oracpa secreted phosphoprotein 1 Homo sapiens