Title : Phosphatidylinositol 4,5-biphosphate (PIP2) modulates interaction of syntaxin-1A with sulfonylurea receptor 1 to regulate pancreatic β-cell ATP-sensitive potassium channels.

Pub. Date : 2014 Feb 28

PMID : 24429282






1 Functional Relationships(s)
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1 Electrophysiological studies of rat beta-cells, INS-1, and SUR1/Kir6.2-expressing HEK293 cells showed that PIP2 dose-dependent activation of KATP currents was uniformly reduced by Syn-1A. Phosphatidylinositol 4,5-Diphosphate potassium inwardly-rectifying channel, subfamily J, member 11 Rattus norvegicus