Title : Differential induction of autophagy by mTOR is associated with abnormal apoptosis in ovarian endometriotic cysts.

Pub. Date : 2014 Apr

PMID : 24319109






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1 Although rapamycin treatment induced autophagy and led to apoptosis promotion, the pro-apoptotic effect of rapamycin was reversed by the addition of 3-MA, suggesting that mTOR inhibition promotes endometriotic cell apoptosis via autophagy induction. 3-methyladenine mechanistic target of rapamycin kinase Homo sapiens