Title : Arg16 ADRB2 genotype increases the risk of asthma exacerbation in children with a reported use of long-acting β2-agonists: results of the PACMAN cohort.

Pub. Date : 2013 Dec

PMID : 24279851






2 Functional Relationships(s)
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1 BACKGROUND: Current evidence suggests that asthma patients with the ADRB2 Arg16 genotype have a poorer response to long-acting beta2-agonists (LABA), but the results remain inconsistent. LABA adrenoceptor beta 2 Homo sapiens
2 CONCLUSION: Children who are homozygous for ADRB2 Arg16 have an increased risk of exacerbations when treated with combined LABA and ICS. LABA adrenoceptor beta 2 Homo sapiens