Pub. Date : 2014 Aug 1
PMID : 24252090
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | AIMS: Adenosine triphosphate (ATP) synthase uses chemiosmotic energy across the inner mitochondrial membrane to convert adenosine diphosphate and orthophosphate into ATP, whereas genetic deletion of Sirt3 decreases mitochondrial ATP levels. | Adenosine Triphosphate | sirtuin 3 | Mus musculus |
| 2 | Site directed mutants demonstrate that OSCP(K139) directs, at least in part, mitochondrial ATP production and mice lacking Sirt3 exhibit decreased ATP muscle levels, increased ATP synthase protein acetylation, and an exercise-induced stress-deficient phenotype. | Adenosine Triphosphate | sirtuin 3 | Mus musculus |