Title : Crystal structure of human cyclin-dependent kinase-2 complex with MK2 inhibitor TEI-I01800: insight into the selectivity.

Pub. Date : 2013 Nov

PMID : 24121337






2 Functional Relationships(s)
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1 Interestingly, the Gly-rich loop of CDK2 formed a beta-sheet that was different from that of MK2. Glycine amyloid beta precursor protein Homo sapiens
2 In MK2, TEI-I01800 changed the secondary structure of the Gly-rich loop from a beta-sheet to an alpha-helix by collision between Leu70 and a p-ethoxyphenyl group at the 7-position and bound to MK2. Glycine amyloid beta precursor protein Homo sapiens