Title : Impact of POR*28 on the pharmacokinetics of tacrolimus and cyclosporine A in renal transplant patients.

Pub. Date : 2014 Feb

PMID : 24061445






1 Functional Relationships(s)
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1 Both CYP3A5 and CYP3A4 are involved in the metabolism of calcineurin inhibitors and recent data show that POR*28 may explain part of the variability observed in tacrolimus (Tac) pharmacokinetics. Tacrolimus cytochrome P450 family 3 subfamily A member 4 Homo sapiens