Title : A functional siRNA screen identifies genes modulating angiotensin II-mediated EGFR transactivation.

Pub. Date : 2013 Dec 1

PMID : 24046455






1 Functional Relationships(s)
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1 Individual knockdown of TRIO, BMX or CHKA attenuated tyrosine phosphorylation of the EGFR by angiotensin II stimulation, but this did not occur following direct stimulation of the EGFR with EGF, indicating that these proteins function between the activated AT1R and the EGFR. Tyrosine angiotensinogen Homo sapiens