Title : Safety and pharmacokinetics of efinaconazole 10% solution in healthy volunteers and patients with severe onychomycosis.

Pub. Date : 2013 Sep

PMID : 24002148






1 Functional Relationships(s)
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1 Efinaconazole is a CYP inhibitor like other azole antifungals, and its lowest ki is 91 ng/mL for CYP2C9, a >130-fold higher concentration than the mean steady state Cmax observed in patients. efinaconazole cytochrome P450 family 2 subfamily C member 9 Homo sapiens