Title : Metabolism of cholesteryl ester lipid droplets in a J774 macrophage foam cell model.

Pub. Date : 1990 Aug 6

PMID : 2386801






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Only a small fraction (less than 10% after 24 h) of the free [3H]cholesterol generated in the lysosomes was esterified by ACAT resulting in a doubling of the cell free cholesterol content. Tritium acetyl-Coenzyme A acetyltransferase 1 Mus musculus
2 ACAT was active as endogenous free [14C]cholesterol was esterified in a linear manner over 24 h and was responsive to the presence of lysosomally-derived cholesterol, as the extent of esterification of the endogenous pool was directly proportional to the mass of [3H]cholesterol generated in the lysosomes. Tritium acetyl-Coenzyme A acetyltransferase 1 Mus musculus