Protein Name acetyl-Coenzyme A acetyltransferase 1
Organism Mus musculus
Gene ID 110446
Gene Symbol

Acat1

UniProt Q8QZT1 (THIL_MOUSE)
Relationships Total Number of functionally related compound(s) : 100
Total Number of Articles : 119
Description

acetyl-Coenzyme A acetyltransferase 1

Gene Summary

Enables acetyl-CoA C-acetyltransferase activity. Predicted to be involved in carboxylic acid catabolic process; ketone body catabolic process; and purine nucleoside bisphosphate metabolic process. Predicted to act upstream of or within fatty acid metabolic process. Located in mitochondrial inner membrane. Is expressed in brain; embryo; heart; liver; and metanephros. Human ortholog(s) of this gene implicated in beta-ketothiolase deficiency and carbohydrate metabolic disorder. Orthologous to human ACAT1 (acetyl-CoA acetyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • acetyl-CoA acetyltransferase, mitochondrial
  • acetoacetyl-CoA thiolase
  • 6330585C21Rik
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Properties