Title : An in silico exploration of the interaction mechanism of pyrazolo[1,5-a]pyrimidine type CDK2 inhibitors.

Pub. Date : 2013 Sep

PMID : 23864105






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1 An in silico exploration of the interaction mechanism of pyrazolo[1,5-a]pyrimidine type CDK2 inhibitors. pyrazolo(1,5-a)pyrimidine cyclin dependent kinase 2 Homo sapiens
2 In the present work, a total of 111 pyrazolo[1,5-a]pyrimidines (PHTPPs) as CDK2/cyclin A inhibitors were studied to conduct three-dimensional quantitative structure-activity (3D-QSAR) analyses. pyrazolo(1,5-a)pyrimidine cyclin dependent kinase 2 Homo sapiens