Pub. Date : 2013
PMID : 23737956
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Moreover, we found that UA effectively promoted NF-kappaB and p300 translocation from cell nuclei to cytoplasm, and attenuated the p300-mediated acetylation of NF-kappaB and CREB2. | ursolic acid | nuclear factor kappa B subunit 1 | Homo sapiens |
| 2 | Moreover, we found that UA effectively promoted NF-kappaB and p300 translocation from cell nuclei to cytoplasm, and attenuated the p300-mediated acetylation of NF-kappaB and CREB2. | ursolic acid | nuclear factor kappa B subunit 1 | Homo sapiens |
| 3 | These results indicate that UA inhibits cell proliferation and induces apoptosis in colon cancer cells through simultaneous modulation of the multiple signaling pathways such as MMP9/CDH1, Akt/ERK, COX-2/PGE2, p300/NF-kappaB/CREB2, and cytochrome c/caspase pathways. | ursolic acid | nuclear factor kappa B subunit 1 | Homo sapiens |