Title : Ursolic acid simultaneously targets multiple signaling pathways to suppress proliferation and induce apoptosis in colon cancer cells.

Pub. Date : 2013

PMID : 23737956






2 Functional Relationships(s)
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1 UA also suppressed colon cancer cell migration by inhibiting MMP9 and upregulating CDH1 expression. ursolic acid matrix metallopeptidase 9 Homo sapiens
2 These results indicate that UA inhibits cell proliferation and induces apoptosis in colon cancer cells through simultaneous modulation of the multiple signaling pathways such as MMP9/CDH1, Akt/ERK, COX-2/PGE2, p300/NF-kappaB/CREB2, and cytochrome c/caspase pathways. ursolic acid matrix metallopeptidase 9 Homo sapiens