Title : Lapatinib inhibits the growth of esophageal squamous cell carcinoma and synergistically interacts with 5-fluorouracil in patient-derived xenograft models.

Pub. Date : 2013 Aug

PMID : 23708506






1 Functional Relationships(s)
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1 Lapatinib in combination with 5-FU had more potent antitumor effects in the primary ESCC xenograft model, and markedly reduced the phosphorylation of EGFR and HER2, compared with lapatinib alone or in combination with oxaliplatin. Fluorouracil erb-b2 receptor tyrosine kinase 2 Homo sapiens