Title : Discovery of a highly potent, nonabsorbable apical sodium-dependent bile acid transporter inhibitor (GSK2330672) for treatment of type 2 diabetes.

Pub. Date : 2013 Jun 27

PMID : 23678871






2 Functional Relationships(s)
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1 Multiple pharmaceutical companies have exploited the physiological link between ASBT and hepatic cholesterol metabolism, which led to the clinical investigation of ASBT inhibitors as lipid-lowering agents. Cholesterol solute carrier family 10 member 2 Homo sapiens
2 Multiple pharmaceutical companies have exploited the physiological link between ASBT and hepatic cholesterol metabolism, which led to the clinical investigation of ASBT inhibitors as lipid-lowering agents. Cholesterol solute carrier family 10 member 2 Homo sapiens